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Topically applied clindamycin phosphate can be absorbed in sufficient amounts to produce systemic effects.
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Topical clindamycin comes in various forms, including gel, lotion, solution and foam.
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Tmp-smx and clindamycin are recommended by current guidelines as options for the management of skin and soft-tissue infections.
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serum level studies following multiple doses of clindamycin hydrochloride for up to 14 days show no evidence of accumulation or altered metabolism of drug.